てんかん（Epilepsy）
てんかんを持つ子供たちを対象にした研究において、ブラックシードには、従来の医薬品による治療では効果のない症状を持つ子供たちに、痙攣を抑制させる効果があると報告されています。
細かい情報へ
Black cumin seed on intractable pediatric seizures.
Akhondian J1, Parsa A, Rakhshande H.
Abstract
BACKGROUND:
Despite the availability and use of numerous
antiepileptic drugs (AEDs), nearly 15% of childhood epilepsy cases are
resistant to treatment. However, in traditional medicine, Nigella Sativa L.
("black cumin seed") has been known for its anticonvulsant effects.
This plant is naturally distributed in Iran and has been widely used as a
natural remedy for a long time. In this study the efficacy of this agent in
reducing the frequency of seizures in childhood refractory epilepsy was
assessed.
MATERIAL/METHODS:
In this double-blinded crossover clinical
trial conducted on children with refractory epilepsy, the aqueous extract of
black seed was administered as an adjunct therapy and the effects were compared
with those of a placebo. Twenty-three children were entered in the study and 20
remained in the study (13 months to 13 years old, 10 boys and 10 girls). All
patients were receiving constant treatment for at least one month before the
study. They received extract (40 mg/kg/8 h) or placebo for a period of four
weeks and between these periods for two weeks they received only their
pre-existing anti-epileptic drugs (AEDs).
RESULTS:
The mean frequency of seizures decreased
significantly during treatment with extract (p<0.05).
CONCLUSIONS:
It can be concluded that the water extract of
Nigella sativa L. has antiepileptic effects in children with refractory
seizures.
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